San Diego Padres
| Date | Player | Last Season Stats | Experience | Age | Old Team | New Team | Notes |
|---|---|---|---|---|---|---|---|
| 03-14-2025 | Miguel Angel Ledesma (P) | - | 0 | 0 | SD | Minor League contract | |
| 03-08-2025 | Jose Iglesias (IF) | .271, 9 HR, 48 RBI in 483 AB. | 11 | 35 | NYM | SD | Minor League contract |
| 03-05-2025 | Wes Benjamin (P) | 0-2, 19 K, 8.74, in 22.2 IP. | 2 | 31 | SD | Minor League contract | |
| 02-24-2025 | Jeronimo Palmeros (P) | - | 0 | 18 | SD | SD | Minor League contract |
| 02-18-2025 | Yuli Gurriel (1B) | .319, 15 HR, 81 RBI in 530 AB. | 7 | 41 | KC | SD | Minor League contract |
| 02-17-2025 | Nick Pivetta (P) | 9-8, 1 Sv,175 K, 4.53, in 155 IP. | 6 | 32 | BOS | SD | four-year |
| 02-13-2025 | Kyle Hart (P) | Minor League | 1 | 32 | SD | one-year | |
| 02-11-2025 | Jason Heyward (OF) | .214, 8 HR, 30 RBI in 323 AB. | 13 | 35 | HOU | SD | one-year |
| 02-09-2025 | Jayvien Sandridge (P) | Minor League | 0 | 26 | SD | NYY | Minor League contract |
| 02-08-2025 | Gavin Sheets (DH/1B) | .250, 11 HR, 34 RBI in 160 AB. | 2 | 29 | CWS | SD | Minor League contract |
| 02-08-2025 | Connor Joe (OF/1B) | .285, 8 HR, 35 RBI in 179 AB. | 3 | 32 | PIT | SD | one-year |
| 02-04-2025 | Nick Ahmed (IF) | .221, 5 HR, 38 RBI in 434 AB. | 9 | 35 | SD | TEX | Minor League contract |
| 02-03-2025 | Ha-seong Kim (IF) | .202, 8 HR, 34 RBI in 267 AB. | 2 | 29 | SD | TB | two-year |
| 01-30-2025 | Elias Diaz (C) | .246, 18 HR, 44 RBI in 338 AB. | 8 | 34 | SD | SD | one-year |
| 01-24-2025 | Ron Marinaccio (P) | Minor League | 1 | 29 | CWS | SD |
Traded
The San Diego Padres acquired pitcher Ron Marinaccio from the Chicago White Sox for cash.
|
| 01-23-2025 | Tanner Scott (P) | 5-4, 70 K, 5.17, in 54 IP. | 6 | 30 | SD | LAD | four-year |
| 01-23-2025 | Jurickson Profar (OF) | .227, 4 HR, 33 RBI in 353 AB. | 9 | 32 | SD | ATL | three-year |
| 01-21-2025 | Martin Perez (P) | 7-8, 97 K, 4.74, in 114 IP. | 11 | 34 | SD | CWS | one-year |
| 01-18-2025 | Kevin Plawecki (C) | .287, 3 HR, 15 RBI in 157 AB. | 8 | 34 | SD | Retired | |
| 01-17-2025 | J.B. Wendelken (P) | 4-3, 2 Sv,39 K, 4.33, in 43.2 IP. | 6 | 32 | SD | Minor League contract | |
| 01-17-2025 | Niko Goodrum (IF/OF) | .214, 9 HR, 33 RBI in 290 AB. | 6 | 33 | BAL | SD | Minor League contract |
| 01-17-2025 | Michael Cervantes (IF) | - | 0 | 24 | SD | Minor League contract | |
| 01-16-2025 | Martin Maldonado (C) | .172, 12 HR, 36 RBI in 373 AB. | 12 | 38 | CWS | SD | Minor League contract |
| 01-16-2025 | Forrest Wall (OF) | Minor League | 0 | 29 | BAL | SD | Minor League contract |
| 01-13-2025 | Donovan Solano (IF) | .280, 7 HR, 31 RBI in 307 AB. | 9 | 37 | SD | SEA | one-year |
| 01-06-2025 | Bryce Johnson (OF) | Minor League | 1 | 29 | SD | PIT | Minor League contract |
| 01-06-2025 | Luis Patino (P) | 5-3, 74 K, 4.31, in 77.1 IP. | 3 | 25 | SD | SD | Minor League contract |
| 01-06-2025 | Rodolfo Duran (C) | Minor League | 0 | 27 | KC | SD | Minor League contract |
| 12-27-2024 | Mike Brosseau (IF) | .187, 5 HR, 18 RBI in 150 AB. | 4 | 31 | NYM | SD | Minor League contract |
| 12-20-2024 | Jake Higginbotham (P) | Minor League | 0 | 29 | DET | SD | Minor League contract |
| 12-17-2024 | Jose Espada (P) | Minor League | 0 | 28 | SD | Minor League contract | |
| 12-13-2024 | Nabil Crismatt (P) | 3-1, 71 K, 3.76, in 81.1 IP. | 3 | 30 | SD | PHI | Minor League contract |
| 12-12-2024 | Logan Gillaspie (P) | Minor League | 1 | 28 | SD | SD | Minor League contract |
| 12-11-2024 | Juan Nunez (P) | - | 0 | 24 | BAL | SD | Rule 5 (Major) |
| 12-11-2024 | C.J. Widger (P) | - | 0 | 26 | SD | SF | Rule 5 (Minor) |
| 12-11-2024 | Eiker Huizi (P) | - | 0 | 24 | DET | SD | Rule 5 (Minor) |
| 12-11-2024 | Andy Thomas (C) | Minor League | 0 | 27 | SF | SD | Rule 5 (Minor) |
| 12-11-2024 | Jake Snider (OF) | Minor League | 0 | 27 | COL | SD | Rule 5 (Minor) |
| 12-05-2024 | Mason McCoy (IF) | Minor League | 0 | 30 | SD | SD | Minor League contract |
| 12-02-2024 | Yonathan Perlaza (IF) | Minor League | 0 | 26 | CHC | SD | Minor League contract |
| 12-02-2024 | Kyle Higashioka (C) | .181, 10 HR, 29 RBI in 193 AB. | 6 | 35 | SD | TEX | two-year |
| 12-01-2024 | Cal Mitchell (OF) | Minor League | 1 | 26 | SD | CWS | Minor League contract |
| 11-26-2024 | Oscar Gonzalez (OF) | Minor League | 1 | 27 | NYY | SD | Minor League contract |
| 11-18-2024 | Harold Chirino (P) | Minor League | 0 | 27 | MIL | SD | Minor League contract |
| 11-15-2024 | Francisco Acuna (IF) | Minor League | 0 | 25 | PIT | SD | Minor League contract |
| 11-14-2024 | Gabe Mosser (P) | Minor League | 0 | 29 | SD | PHI | Minor League contract |
| 11-13-2024 | Trenton Brooks (1B) | Minor League | 0 | 29 | SF | SD | Minor League contract |
| 11-11-2024 | Eduarniel Nunez (P) | Minor League | 0 | 26 | CHC | SD | Minor League contract |
| 11-04-2024 | Carl Edwards Jr. (P) | 0-0, 6 K, 11.12, in 5.2 IP. | 8 | 33 | SD | Free agent | |
| 10-31-2024 | David Peralta (OF) | .259, 8 HR, 63 RBI in 487 AB. | 9 | 37 | SD | Free agent |